ANTXR1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of ANTXR1.

Supplier:  Abnova Corporation PAB3943

Catalog No. 89-131-215

Description

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq

Specifications

• Antigen: ANTXR1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of ANTXR1.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: NP_115584;Q9H6X2
• Gene Symbols: ANTXR1
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y382 of human ANTXR1.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:10-50) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Gene: ANTXR1
• Gene Alias: ATR/FLJ10601/FLJ11298/FLJ21776/TEM8
• Host Species: Rabbit
• Purification Method: Protein A purification
• Regulatory Status: RUO
• Gene ID (Entrez): 84168
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only