CAD (phospho T456), Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human CAD.
Supplier: Abnova Corporation PAB29236
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. [provided by RefSeq
|Rabbit polyclonal antibody raised against synthetic phosphopeptide of human CAD.
|In PBS, pH 7.4 (without mg2+ and Ca2+), (50% glycerol, 0.02% sodium azide)
|Immunohistochemistry (PFA fixed)
|Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
|Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T456 of human CAD.
|This antibody detects endogenous levels of CAD only when phosphorylated at threonine 456.
|Store at -20°C.
Avoid repeated freezing and thawing.
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