CCR8 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic peptide of CCR8.
Manufacturer: Abnova Corporation PAB16335
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq
|Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) The optimal working dilution should be determined by the end user.|
|A synthetic peptide (conjugated with KLH) corresponding to human CCR8.|
|Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
|3rd Cytoplasmic domain of human.|
|Immunohistochemistry (PFA fixed)|
|Rabbit polyclonal antibody raised against synthetic peptide of CCR8.|
|In PBS (0.09% sodium azide)|
For Research Use Only