CXCR4 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of CXCR4.

Manufacturer:  Abnova Corporation PAB26089

Catalog No. 89-127-729

Description

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq

Specifications

• Antigen: CXCR4
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (7 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: CXCR4
• Format: Liquid
• Gene Symbols: CXCR4
• Immunogen: A synthetic peptide corresponding to 16 amino acids at N-terminus of human CXCR4.
• Quantity: 50 ug
• Storage Requirements: Store at 4°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Monoclonal or Polyclonal: Polyclonal
• Test Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

• Applications: Immunohistochemistry (PFA fixed)
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CXCR4.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: P61073
• Gene Alias: CD184|D2S201E|FB22|HM89|HSY3RR|LAP3|LCR1|LESTR|NPY3R|NPYR|NPYRL|NPYY3R|WHIM
• Host Species: Rabbit
• Purification Method: Immunoaffinity chromatography
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7852
• Target Species: Human

For Research Use Only