DUSP6, Rabbit, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of DUSP6.
Supplier: Abnova Corporation PAB4131
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
|Rabbit polyclonal antibody raised against synthetic peptide of DUSP6.|
|In PBS (0.09% sodium azide)|
|A synthetic peptide (conjugated with KLH) corresponding to internal region of human DUSP6.|
|ELISA, Western Blot|
|ELISA (1:1000) Western Blot (1:100-500) The optimal working dilution should be determined by the end user.|
|Protein G purification|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok
For Research Use Only