ESR1 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of ESR1.

Supplier:  Abnova Corporation PAB26653

Catalog No. 89-128-291

Description

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq]

Sequence: S-P- Sp-P-L

Specifications

• Antigen: ESR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
• Gene: ESR1
• Gene Alias: DKFZp686N23123/ER/ESR/ESRA/Era/NR3A1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2099
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody raised against synthetic peptide of ESR1.
• Formulation: In PBS (without mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Accession No.: P03372
• Gene Symbols: ESR1
• Immunogen: A synthetic peptide corresponding to residues surrounding S106 of human ESR1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Form: Liquid

For Research Use Only