ESR1 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic peptide of ESR1.
Manufacturer: Abnova Corporation PAB26654
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeqSequence: Q-L-Sp-P-F
|Rabbit polyclonal antibody raised against synthetic peptide of ESR1.|
|In PBS (without mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)|
|Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot|
|Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user.|
|A synthetic peptide corresponding to residues surrounding S118 of human ESR1.|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
For Research Use Only