GFRA2 Rabbit anti-Human, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of GFRA2.

Supplier:  Abnova Corporation PAB0694

Catalog No. 89-114-346

Description

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: PRVEKTPSLPDDLSD

Specifications

• Antigen: GFRA2
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of GFRA2.
• Formulation: Lyophilized from PBS
• Gene Accession No.: O00451
• Gene Symbols: GFRA2
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to amino acids 376-390 of human GFRA2.
• Regulatory Status: RUO
• Gene ID (Entrez): 2675
• Content And Storage: Store at 4°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

• Applications: Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:500-1:1000) Western Blot (1:500-1:1000) The optimal dilution should be determined by the end user.
• Gene: GFRA2
• Gene Alias: GDNFRB/NRTNR-ALPHA/NTNRA/RETL2/TRNR2
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Form: Lyophilized

For Research Use Only