GRIN2B (phospho Y1474), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of GRIN2B.

Supplier:  Abnova Corporation PAB12171

Catalog No. 89-115-666

Description

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq

Sequence: HVYpEK

Specifications

• Antigen: GRIN2B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user.
• Gene: GRIN2B
• Gene Alias: MGC142178/MGC142180/NMDAR2B/NR2B/hNR3
• Host Species: Rabbit
• Purification Method: Immunoaffinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 2904
• Target Species: Human, Mouse, Rat
• Form: Liquid

• Applications: Immunofluorescence
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of GRIN2B.
• Formulation: In PBS (without mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Accession No.: Q13224
• Gene Symbols: GRIN2B
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y1474 of human GRIN2B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: NMDAR2B (phospho-Tyr1474) antibody detects endogenous levels of NMDAR2B only when phosphorylated at Tyr1474.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only