IGF1R Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of IGF1R.
Manufacturer: Abnova Corporation PAB18506
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq
|Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:40000) The optimal working dilution should be determined by the end user.|
|A synthetic peptide corresponding to residues surrounding Y1346 of human IGF1R.|
|This antibody is specific to IGF1R.|
|ELISA, Immunohistochemistry (PFA fixed), Western Blot|
|Rabbit polyclonal antibody raised against synthetic peptide of IGF1R.|
|In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)|
|Human, Mouse, Rat|
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