IGF1R Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of IGF1R.

Supplier:  Abnova Corporation PAB18506

Catalog No. 89-120-068

Description

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq

Specifications

• Antigen: IGF1R
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:40000) The optimal working dilution should be determined by the end user.
• Gene: IGF1R
• Gene Symbols: IGF1R
• Immunogen: A synthetic peptide corresponding to residues surrounding Y1346 of human IGF1R.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody is specific to IGF1R.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody raised against synthetic peptide of IGF1R.
• Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Alias: CD221/IGFIR/JTK13/MGC142170/MGC142172/MGC18216
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 3480
• Target Species: Human, Mouse, Rat
• Form: Liquid

For Research Use Only