IL4R Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of IL4R.
Supplier: Abnova Corporation PAB26977
This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Two transcript variants encoding different isoforms, a membrane-bound and a soluble form, have been found for this gene. [provided by RefSeq
|Rabbit polyclonal antibody raised against synthetic peptide of IL4R.
|In PBS, pH 7.2 (0.09% sodium azide)
|Antigen affinity purification
|Immunofluorescence, Western Blot
|Western Blot (1:500-1:1000) Immunofluorescence (1:50-1:200) The optimal working dilution should be determined by the end user.
|A synthetic peptide corresponding to human IL4R.
|IL4R polyclonal antibody detects endogenous levels of IL4R protein.
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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