LCK Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic peptide of LCK.
Manufacturer: Abnova Corporation PAB18185
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq
|Rabbit polyclonal antibody raised against synthetic peptide of LCK.|
|In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)|
|A synthetic peptide corresponding to human LCK.|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|This antibody is specific to LCK.|
|ELISA, Immunofluorescence, Western Blot|
|Western Blot (1:500-1:1000) Immunofluorescence (1:500-1:1000) ELISA (1:5000) The optimal working dilution should be determined by the end user.|
|Human, Murine, Rat|
For Research Use Only