LCK Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of LCK.

Manufacturer:  Abnova Corporation PAB18185

Catalog No. 89-119-757

Description

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq

Specifications

• Antigen: LCK
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody raised against synthetic peptide of LCK.
• Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Format: Liquid
• Gene Symbols: LCK
• Immunogen: A synthetic peptide corresponding to human LCK.
• Quantity: 100 ug
• Storage Requirements: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Monoclonal or Polyclonal: Polyclonal
• Test Specificity: This antibody is specific to LCK.

• Applications: ELISA, Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) Immunofluorescence (1:500-1:1000) ELISA (1:5000) The optimal working dilution should be determined by the end user.
• Gene: LCK
• Gene Alias: YT16|p56lck|pp58lck
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3932
• Target Species: Human, Murine, Rat

For Research Use Only