MMP24, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of MMP24.

Supplier:  Abnova Corporation PAB4789

Catalog No. 89-131-577

Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. [provided by RefSeq

Specifications

• Antigen: MMP24
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of MMP24.
• Formulation: In PBS (0.09% sodium azide)
• Gene Alias: MMP25/MT-MMP5/MT5-MMP
• Host Species: Rabbit
• Purification Method: Protein G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 10893
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: ELISA (1:1000) Western Blot (1:100-500) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
• Gene: MMP24
• Gene Symbols: MMP24
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to internal region of human MMP24.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

For Research Use Only