PARP1 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of PARP1.

Manufacturer:  Abnova Corporation PAB27166

Catalog No. 89-128-820

Description

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq

Specifications

• Antigen: PARP1
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody raised against synthetic peptide of PARP1.
• Formulation: In PBS, pH 7.2 (0.05% sodium azide)
• Format: Liquid
• Gene Symbols: PARP1
• Immunogen: A synthetic peptide corresponding to human PARP1.
• Quantity: 100 uL
• Storage Requirements: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Monoclonal or Polyclonal: Polyclonal
• Test Specificity: PARP1 polyclonal antibody detects endogenous levels of PARP1 protein.

• Applications: Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Gene: PARP1
• Gene Alias: ADPRT|ADPRT1|PARP|PARP-1|PPOL|pADPRT-1
• Host Species: Rabbit
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 142
• Target Species: Human, Murine

For Research Use Only