PDGFRB (phospho Y857), Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic phosphopeptide of PDGFRB.
Manufacturer: Abnova Corporation PAB1244
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq
|Western Blot (1:1800) The optimal working dilution should be determined by the end user.|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Rabbit polyclonal antibody raised against synthetic phosphopeptide of PDGFRB.|
|In HEPES, 150mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)|
|Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y857 of human PDGFRB.|
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