PRKCB (phospho S660), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic phosphopeptide of PRKCB.
Manufacturer: Abnova Corporation PAB17906
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
|Rabbit polyclonal antibody raised against synthetic phosphopeptide of PRKCB.|
|In PBS (50% glycerol, 1% BSA, 0.02% sodium azide)|
|This antibody recognizes several Phosphorylated PKC (Ser660) isoforms of human, mouse, and rat origins.|
|Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
|Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.|
|Synthetic phosphopeptide corresponding to residues surrounding S660 of human PRKCB.|
|Human, Mouse, Rat|
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For Research Use Only