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PRKCG Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of PRKCG.

Manufacturer:  Abnova Corporation PAB12321

Catalog No. 89-115-716


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Description

Description

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). [provided by RefSeq

Specifications

Specifications

PRKCG
Unconjugated
Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
PRKCG
MGC57564|PKC-gamma|PKCC|PKCG|SCA14
Rabbit
IgG
100 ug
Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water to a concentration of 500μg/mL
Polyclonal
Identical to the related rat and mouse sequence.
Western Blot
Rabbit polyclonal antibody raised against synthetic peptide of PRKCG.
Lyophilized from 0.9mg NaCl, 0.2mg Na2HPO4 (5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)
Lyophilized
PRKCG
A synthetic peptide corresponding to amino acids at C-terminus of human PRKCG.
Affinity purification
RUO
Primary
5582
Human, Murine, Rat
SDS
Documents
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