STAM, Rabbit, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of STAM.
Manufacturer: Abnova Corporation PAB1751
This gene was identified by the rapid tyrosine-phosphorylation of its product in response to cytokine stimulation. The encoded protein contains a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). This protein associates with JAK3 and JAK2 kinases via its ITAM region, and is phosphorylated by the JAK kinases upon cytokine stimulation, which suggests the function of this protein is as an adaptor molecule involved in the downstream signaling of cytokine receptors. HGS/HRS (hepatocyte grwoth factor-regulated tyrosine kinase substrate) has been found to bind and counteract the function of this protein. [provided by RefSeq
|Rabbit polyclonal antibody raised against synthetic peptide of STAM.|
|In PBS (0.09% sodium azide)|
|Protein G purification|
|ELISA, Immunohistochemistry, Western Blot|
|Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.|
|A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human STAM.|
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