STAT3 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of STAT3.
Supplier: Abnova Corporation PAB26632
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeqSequence: A-P-Yp-L-K
|Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user.
|A synthetic peptide corresponding to residues surrounding Y705 of human STAT3.
|Human, Mouse, Rat
|Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
|Rabbit polyclonal antibody raised against synthetic peptide of STAT3.
|In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
For Research Use Only