TNFSF8, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of TNFSF8.

Manufacturer:  Abnova Corporation PAB26949

Catalog No. 89-128-595

Description

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. [provided by RefSeq

Specifications

• Antigen: TNFSF8
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody raised against synthetic peptide of TNFSF8.
• Formulation: In PBS, pH 7.2 (0.05% sodium azide)
• Format: Liquid
• Gene Symbols: TNFSF8
• Immunogen: A synthetic peptide corresponding to human TNFSF8.
• Quantity: 100 uL
• Storage Requirements: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Monoclonal or Polyclonal: Polyclonal
• Test Specificity: TNFSF8 polyclonal antibody detects endogenous levels of TNFSF8 protein.

• Applications: Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) Immunofluorescence (1:50-1:200) The optimal working dilution should be determined by the end user.
• Gene: TNFSF8
• Gene Alias: CD153|CD30L|CD30LG|MGC138144
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 944
• Target Species: Human, Murine

For Research Use Only