TRAF3 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of TRAF3.

Supplier:  Abnova Corporation PAB12955

Catalog No. 89-116-216

Description

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq

Specifications

• Antigen: TRAF3
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of TRAF3.
• Formulation: In PBS (0.02% sodium azide)
• Gene Alias: CAP-1/CD40bp/CRAF1/LAP1
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Liquid

• Applications: Immunocytochemistry, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: TRAF3
• Gene Symbols: TRAF3
• Immunogen: A synthetic peptide corresponding to N-terminus 15 amino acids of human TRAF3.
• Regulatory Status: RUO
• Gene ID (Entrez): 7187
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only