WT1, Rabbit, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic peptide of WT1.
Manufacturer: Abnova Corporation PAB11849
This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq
|Rabbit polyclonal antibody raised against synthetic peptide of WT1.|
|In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)|
|A synthetic peptide corresponding to C-terminus of human WT1.|
|Store at 4°C.|
|Immunohistochemistry (PFA fixed)|
|Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok
For Research Use Only