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WT1, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of WT1.

Manufacturer:  Abnova Corporation PAB11849

Catalog No. 89-115-423

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq

Specifications

Specifications

WT1
Lot specific
Rabbit polyclonal antibody raised against synthetic peptide of WT1.
In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Liquid
WT1
A synthetic peptide corresponding to C-terminus of human WT1.
100 uL
Store at 4°C.
Polyclonal
Human
Immunohistochemistry (PFA fixed)
Unconjugated
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
WT1
GUD|WAGR|WIT-2|WT33
Rabbit
Immunoaffinity purification
RUO
Primary
7490
SDS
Documents
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