RAD23B Mouse anti-Human, Clone: OTI12C10, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526702
DescriptionThe protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|HHR23B, HR23B, P58, RAD23, yeast homolog of, B, UV excision repair protein RAD23 homolog B, XP-C repair complementing complex 58 kDa, XP-C repair complementing protein, XP-C repair-complementing complex 58 kDa protein|
|-20° C, Avoid Freeze/Thaw Cycles|
|Human recombit protein fragment corresponding to amino acids 1-253 of RAD23B produced in E.coli|
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