RAD50 Monoclonal Antibody (13B3), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA123269

Catalog No. 01-950-107

Description

Recommended positive controls: HeLa, HeLa nuclear extract.

Rad50-13B3 recognizes human Rad50, a 153a protein involved in DNA double strand break repair. Rad50 is associated with Mre11 and p95 (Nibrin) to form a multiprotein complex involved in the double strand break repair process. Upon DNA damage, Rad50 and Mre11 redistribute and are co-localized within the nucleus of damaged cells.

Specifications

• Antigen: RAD50
• Classification: Monoclonal
• Concentration: 1.7 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P70388, Q92878, Q9JIL8
• Gene Symbols: RAD50
• Immunogen: Amino acids 1-425 of Rad50 expressed in E. coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Non-human Primate, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, In vitro Assay, Western Blot
• Clone: 13B3
• Conjugate: Unconjugated
• Gene: RAD50
• Gene Alias: 153 kDa protein; DNA repair protein RAD50; hRad50; hsRAD50; I79_004319; mRad50; Mrell; MRX complex DNA-binding subunit; N0872; NBSLD; Rad50; RAD50 2; RAD50 double strand break repair protein; RAD50 homolog (S. cerevisiae); RAD50 homolog, double strand break repair protein; RAD50 PEN; RAD502; RAD50-2; RAD50-3; Rad50l; YNL250W
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 10111, 19360, 64012
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov