RAD50 Rabbit anti-Human, Polyclonal , Abnova™
Rabbit polyclonal antibody raised against recombinant human RAD50.
Manufacturer: Abnova Corporation PAB29446
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq]Sequence: ELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYYKTLDQAIMKFHSMKMEEINKIIRDLWRSTYRGQDIEYIEIRSDADENVSASDKRRNYNYRVV
|Immunohistochemistry (1:50-1:200) Immunofluorescence (1-4 ug/mL) The optimal working dilution should be determined by the end user.|
|Recombinant protein corresponding to human RAD50.|
|Antigen affinity purification|
|Immunofluorescence, Immunohistochemistry (PFA fixed)|
|Rabbit polyclonal antibody raised against recombinant human RAD50.|
|In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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