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RAD51 Mouse anti-Human, Clone: 13E4, Abnova™

Mouse monoclonal antibody raised against human RAD51.

Manufacturer:  Abnova Corporation MAB12627

Catalog No. 89-934-840


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Description

Description

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

Specifications

RAD51
13E4
Mouse monoclonal antibody raised against human RAD51.
In PBS, pH 7.2.
BRCC5/HRAD51/HsRad51/HsT16930/RAD51A/RECA
Mouse
IgG1
50 uL
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Monoclonal
Human
Immunohistochemistry (PFA fixed), Western Blot
Unconjugated
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) Western Blot The optimal working dilution should be determined by the end user.
Liquid
RAD51
Recombinant protein corresponding to human RAD51.
Protein G purification
RUO
Primary
5888
SDS
Documents
Product Certifications
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