RAD51B Mouse anti-Human, Clone: OTI7H4, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525683
DescriptionThe DNA repair proteins Rad50, Rad51A-D, Rad52 and Rad54 A and B are key components of the double-strand break repair pathway (DSBR). The process of homologous recombination is a major DNA repair pathway that operates on DNA double-strand breaks to promote error-free repair. Human Rad51 protein assembles on a DNA molecule through cooperative binding and forms a long filament for homologous recombination. In addition to Rad51 protein, five paralogs have been identified in vertebrates, Rad51B, Rad51C, Rad51D, Xrcc2 and Xrcc3. Rad51B is a widely expressed protein that is involved in the repair of double-stranded DNA breaks that can arise during DNA replication. It can form a dimer with Rad51C and this complex shows single-stranded DNAdependent ATPase activity.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|DNA repair protein RAD51 homolog 2, MGC34245, R51H2REC2hREC2, RAD51 (S. cerevisiae)-like 1, RAD51 homolog B, RAD51B, RAD51-like 1 (S. cerevisiae), RAD51-like protein 1, RecA-like protein, recombination repair protein|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot|
|Human recombit protein fragment corresponding to amino acids 119-346 of RAD51L1 produced in E.coli|
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