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RAD54L2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550258

Catalog No. PA550258


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Description

Description

The antibody detects endogenous levels of total RAD54L2 protein.

Adrenergic receptors (ARs) include four general types (a1, a2, b1 and b2) that are found in different target tissues and differ in their affinities and responses to various agonists and antagonists. The coupling of ARs to specific intracellular effectors is mediated through diverse heterotrimeric G proteins. ARs play a critical role in the development of prostate cancer, and transcriptional activity of AR is partly regulated by coregulatory proteins. RAD54L2 (RAD54-like 2), also known as ARIP4 (androgen receptor-interacting protein 4), HSPC325 or SRISNF2L, is a 1,467 amino acid nuclear protein belonging to the SNF2/RAD54 helicase family that consists of one helicase ATP-binding domain and a helicase C-terminal domain. RAD54L2 is a DNA helicase that regulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. RAD54L2 is post-translationally sumoylated or phosphorylated upon DNA damage.
Specifications

Specifications

RAD54L2
Polyclonal
Unconjugated
RAD54L2
Liquid
RAD54L2
Fusion protein corresponding to residues near the C terminal of human RAD54-like 2 (S. cerevisiae)
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
2.7 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q9Y4B4
ARIP4, KIAA0809
Rabbit
IgG
100 μL
-20°C
Primary
23132
Documents
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