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RADIL Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 202841AP

Catalog No. 50-173-2810


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Description

Description

Radil is a broadly expressed adapter protein that contains a RA-like domain, a PDZ domain and a DIL domain. Like RAPL and RIAM, Radil interacts preferentially with active GTP-bound Rap1, and overexpression of Radil enhances integrin-mediated adhesion. In addition, Radil knock down inhibits cell-substrate adhesion in HT1080, AD293, and NMuMG cells and results in migration defects in SW1353 and zebrafish neural crest cells. Radil regulates neutrophil adhesion by specifically enhancing beta2-integrin activation, as well as focal adhesion kinase (FAK) and paxillin phosphorylation.
Specifications

Specifications

RADIL
0.43 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q96JH8
KIAA1849, RADIL
Rabbit
IgG
150 μL
-20°C
Primary
55698
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Unconjugated
RADIL
Liquid
RADIL
RADIL Fusion Protein Ag13996
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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