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Thermo Scientific™ Lab Vision™ Raf-1 (Phospho-specific) Ab-2, Rat Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ Raf-1 (Phospho-specific) Ab-2, Rat Monoclonal Antibody.

Specifications

Antigen Raf-1 (Phospho-specific) Ab-2
Clone pS338[DPR/2/2A/3A]
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
RT1732R1
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Thermo Scientific™
RT1732R1
Ready-to-use for IHC (UVLP) 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Provide accurate, reproducible results with the Thermo Scientific™ Raf-1 (Phospho-specific) Ab-2, Rat Monoclonal Antibody.

Raf1 is an important mediator of signal transduction pathway. It is activated through activation by Src and protein kinase C. It further phosphorylates Mek1 and cdc25. It can bind to GTP-bound Ras through N-terminal domain. It also interacts with hsp90 and 14.3.3 family of proteins.

Host Species: Rat

Clone: pS338[DPR/2/2A/3A]

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: GQRDS™SYY™WEIEAS

Immunogen: A synthetic peptide corresponding to aa GQRDS™SYY™WEIEAS

Molecular Weight: 74kDa

Positive Control: Tonsil

Cellular Localization: Nuclear Ab-2 binds to phosphorylated serine residue at aa338. It does not bind to unactivated Raf-1 or Raf-1 phosphorylated at Y341 and S339.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO


General References:

1. Mason C S, et al. (1999) EMBO J, 18:2137-2148.

Specifications

Specifications

Raf-1 (Phospho-specific) Ab-2
Immunohistochemistry (Paraffin)
Unconjugated
RUO
Primary
IgG1
pS338[DPR/2/2A/3A]
Monoclonal
Rat
Signal Transduction
A synthetic peptide corresponding to aa GQRDSasteriskSYYasteriskWEIEAS
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