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RALB Mouse anti-Canine, Human, Mouse, Non-human primate, Rat, Clone: OTI2C4, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526219

Catalog No. PIMA526219


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Description

Description

Ral A and Ral B constitute a distinct subfamily of Ras-related GTPases (i.e., GDP/GTP binding proteins). Ral proteins are activated by a unique nucleotide exchange factor, Ral GDS, and deactivated by a distinct GTPase-activating protein. Unlike Ras proteins, Ral A and Ral B fail to induce transformed foci when activated variants are expressed in various recipient cells. A potential downstream target of Ral, designated Ral BP-1, has been shown to contain a Rho-GTPase-activating domain. This Rho-GTPase-activating domain interacts preferentially with the Rho family member Cdc42. A Ras/Ral signaling pathway has been reported to mediate phospholipase D (PLD) activation by v-Src, thus indicating PLD as another downstream target of Ral A.
Specifications

Specifications

RALB
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q9JIW9, P36860, Q4R379, P11234
GTP binding protein; OTTHUMP00000204385; OTTHUMP00000207264; RAS-like protein B; ras-related protein Ral-B
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
101925782, 116546, 483881, 5899, 64143
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI2C4
Unconjugated
RALB
Liquid
RALB
Full length human recombit protein of RALB produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Canine, Human, Mouse, Non-human primate, Rat
Documents
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