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RAMP1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550253

Catalog No. PA550253


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Description

Description

The antibody detects endogenous levels of total RAMP1 protein.

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
Specifications

Specifications

RAMP1
Polyclonal
Unconjugated
RAMP1
Liquid
RAMP1
Fusion protein corresponding to a region derived from internal residues of human Receptor (G protein-coupled) activity modifying protein 1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
0.4 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
O60894, Q9WTJ5
RAMP1
Rabbit
IgG
100 μL
-20°C
Primary
10267, 51801
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