Invitrogen™ RANBP1 Monoclonal Antibody (OTI8E1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA527490

Catalog No. PIMA527490

Description

RANBP1 Monoclonal Antibody for Western Blot

Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.

Specifications

• Antigen: RANBP1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P43487
• Gene Symbols: RANBP1
• Immunogen: Full length human recombinant protein of RANBP1 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot
• Clone: OTI8E1
• Conjugate: Unconjugated
• Gene: RANBP1
• Gene Alias: HpaII tiny fragments locus 9A; hpaII tiny fragments locus 9a protein; Htf9a; Htf9-a; Htf9-a/RanBP1; RAN binding protein 1; ran-binding protein 1; RANBP1; RANG; Ran-specific GTPase-activating protein; testis secretory sperm-binding protein Li 221n
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5902
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid