RANBP1 Mouse anti-Human, Clone: OTI8E1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527490
DescriptionRan/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|HTF9A, ran-binding protein 1, ran-specific GTPase-activating protein|
|-20° C, Avoid Freeze/Thaw Cycles|
|Full length human recombit protein of RANBP1 produced in HEK293T cell|
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