RANBP9 Mouse anti-Human, Clone: 3C3, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524871
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B.
|Recombit full length Human RanBP9.|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.4|
|BPM-L; BPM90; Ran-binding protein M; RanBPM; RanBP7; BPM-L; BPM90; RANBPM; RanBP7|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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