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RANGAP1 Mouse anti-Canine, Human, Rat, Clone: OTI1B4, liquid, TrueMAB™
Mouse Monoclonal Antibody
Supplier: OriGene TA501265S
Description
RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1, 000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.Specifications
RANGAP1 | |
Monoclonal | |
0.81 mg/mL | |
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
P46060 | |
Rangap1 | |
Full length human recombit protein of human RANGAP1 produced in HEK293T cell. | |
30 μL | |
Primary | |
Canine, Human, Rat | |
Antibody | |
IgG2a |
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
OTI1B4 | |
Unconjugated | |
RANGAP1 | |
Fug1, RANGAP, SD | |
Mouse | |
Affinity Chromatography | |
RUO | |
362965, 481234, 5905 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
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