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RANGAP1 Mouse anti-Canine, Human, Rat, Clone: OTI1B4, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA501265

Catalog No. 50-167-2408


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Description

Description

RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1, 000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.
Specifications

Specifications

RANGAP1
Monoclonal
0.81 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P46060
Fug1, RANGAP, SD
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
362965, 481234, 5905
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI1B4
Unconjugated
RANGAP1
Liquid
RANGAP1
Full length human recombit protein of human RANGAP1 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Canine, Human, Rat
Documents
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