RANGAP1 Mouse anti-Canine, Human, Rat, Clone: OTI1B4, liquid, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene TA501265
DescriptionRanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1, 000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide|
|Fug1, RANGAP, SD|
|-20° C, Avoid Freeze/Thaw Cycles|
|362965, 481234, 5905|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of human RANGAP1 produced in HEK293T cell.|
|Canine, Human, Rat|
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