RANK Monoclonal Antibody (9A725), PE, Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA141015

Catalog No. 01-676-435

Description

This antibody recognizes an epitope located between amino acid residues 330-427 of human RaNK. Suggested positive control: Raw.

RANK is a member of the tumor necrosis factor receptor (TNFR) family. The full length mouse RANK cDNA encodes a type I transmembrane protein with an extracellular and a cytoplasmic domain. The extracellular domain contains two potential N-linked glycosylation sites. RANK shares significant amino acid homology with other members of the TNFR family in its extracellular four cysteine-rich repeats. Human and murine RANK share 81% amino acid identity in their extracellular domains.

Specifications

• Antigen: RANK
• Classification: Monoclonal
• Concentration: 0.33 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: O35305, Q9Y6Q6
• Gene Symbols: TNFRSF11A
• Immunogen: Fusion protein containing residues 326-616 of human RANK.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Avian, Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 9A725
• Conjugate: PE
• Gene: TNFRSF11A
• Gene Alias: CD265; FEO; LOH18CR1; loss of heterozygosity, 18, chromosomal region 1; Ly109; mRANK; ODFR; OFE; OPTB7; Osteoclast differentiation factor receptor; OSTS; Paget disease of bone 2; PDB2; Rank; receptor activator of NF-kappaB; receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; RGD1563614; TNF receptor superfamily member 11a; Tnfrsf11a; TRANCER; TRANCE-R; tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, NFKB activator
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 21934, 498206, 8792
• Content And Storage: 4° C, store in dark
• Form: Liquid