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RANKL Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 234081AP

Catalog No. 50-173-4069


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Description

Description

sRANKL is a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis.
Specifications

Specifications

RANKL
0.28 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O14788
CD254, hRANKL2, ODF, OPGL, OPTB2, Osteoprotegerin ligand, RANKL, sOdf, TNFSF11, TRANCE
Rabbit
IgG
150 μL
-20°C
Primary
8600
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
TNFSF11
Liquid
TNFSF11
RANKL Fusion Protein Ag19975
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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