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RAR-gamma Monoclonal Antibody (4 gamma-7A11), Active Motif™
Mouse Monoclonal Antibody
$123.90 - $377.60
Specifications
| Antigen | RAR-gamma |
|---|---|
| Clone | 4 gamma-7A11 |
| Concentration | 1 mg/mL |
| Applications | Gel Shift, Immunohistochemistry, Western Blot |
| Classification | Monoclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-199-3012
|
Active Motif
39974 |
10 μg |
Each for $123.90
|
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50-199-3011
|
Active Motif
39973 |
100 μg |
Each for $377.60
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Description
Retinoic acid, a metabolite of vitamin A, is necessary for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. Retinoic acid functions through its interaction with the nuclear protein, retinoic acid receptor (RAR). RAR belongs to the steroid and thyroid hormone superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. RAR exists as three major subtypes: alpha, beta and gamma. Two main isoforms of RAR gamma exist: RAR gamma-1 has been found to be predominantly expressed in skin, while RAR gamma-2 has been found early in embryogenesis and in embryonal carcinoma cells. RAR gamma is also known as RARD. The corresponding gene for the retinoic acid receptor gamma 1 is NR1B3.Specifications
| RAR-gamma | |
| 1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8 | |
| NR1B3; Nuclear receptor subfamily 1 group B member 3; RAR gamma 2; RAR Gamma-1; RARC; RARD; Rarg; RAR-gamma; RARgamma2; retinoic acid nuclear receptor gamma variant 1; retinoic acid nuclear receptor gamma variant 2; Retinoic acid receptor gamma; retinoic acid receptor gamma 4; retinoic acid receptor, gamma | |
| Rarg | |
| IgG1 κ | |
| Protein G | |
| Antibody |
| 4 gamma-7A11 | |
| Gel Shift, Immunohistochemistry, Western Blot | |
| Unconjugated | |
| Mouse | |
| Human | |
| P13631 | |
| 5916 | |
| This RAR-gamma antibody was raised against a recombinant protein corresponding to amino acids 428-441 (F-region) of human RAR gamma. | |
| Primary | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Rarg |
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