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RASAL1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550867

Catalog No. PA550867


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Description

Description

The antibody detects endogenous levels of total RASAL1 protein.

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described
Specifications

Specifications

RASAL1
Polyclonal
Unconjugated
RASAL1
Liquid
RASAL1
Fusion protein corresponding to residues near the N terminal of human RAS protein activator like 1 (GAP1 like)
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
1.2 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
O95294
RASAL
Rabbit
IgG
100 μL
-20°C
Primary
8437
Documents
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