RASSF1 Mouse anti-Human, Clone: OTI2B11, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525425
DescriptionThis gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|123F2, NORE2A, RASSF1A, RDA32, REH3P21, WUGSC:H_LUCA12.5, cardiac-specific ras association domain family 1 protein, pancreas-specific ras association domain family 1 protein, ras association domain-containing protein 1, tumor suppressor protein RDA32|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of RASSF1 produced in E.coli|
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