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CD195 Rat anti-Mouse, BUV737, Clone: C34-3448, BD

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 565298

Catalog No. BDB565298

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

The C34-3448 monoclonal antibody specifically binds to CD195 which is also known as, C-C chemokine receptor type 5 (CCR5). CD195 is a seven transmembrane-spanning G-protein-coupled receptor that belongs to the β- chemokine receptor family. CD195 regulates lymphocyte chemotaxis activation and transendothelial migration during inflammation. It signals in response to at least three chemokines: CCL3/MIP-1 α , CCL4/MIP-1 β , and CCL5/RANTES. CD195 is expressed on macrophages and some T-lymphocytes.

Due to spectral differences between labeled cells and beads, using BD™ CompBeads can result in incorrect spillover values when used with BD Horizon BUV737 reagents. Therefore, the use of BD CompBeads or BD CompBeads Plus to determine spillover values for these reagents is not recommended. Different BUV737 reagents (e.g., CD4 vs. CD45) can have slightly different fluorescence spillover therefore, it may also be necessary to use clone specific compensation controls when using these reagents.

Specifications

Specifications

CD195
C34-3448
Brilliant Ultraviolet 737
Aqueous buffered solution containing ≤0.09% sodium azide.
Rat
IgG2c, κ
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
0.2mg/mL
Ccr5; chemokine (C-C) receptor 5; C-C CKR-5; CC-CKR-5; CCR-5; AM4-7
Affinity Purified
Mouse CCR5 a.a. 9-30
Affinity Chromatography
RUO
Primary
Murine
Documents
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