Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Rat anti-Endorepellin/Perlecan/Heparan Sulfate Proteoglycan, Clone: SPM255, Novus Biologicals™

Rat Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2444490.02MG

 View more versions of this product

Catalog No. NBP24444900


Add to cart

Description

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Monoclonal antibody specifically detects Endorepellin/Perlecan/Heparan Sulfate Proteoglycan in Human, Mouse, Porcine, Fish, Monkey, Primate samples. It is validated for Flow Cytometry, Immunohistochemistry-Paraffin, Immunofluorescence.
Specifications

Specifications

Endorepellin/Perlecan/Heparan Sulfate Proteoglycan
SPM255
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
basement membrane-specific heparan sulfate proteoglycan core protein, endorepellin (domain V region), heparan sulfate proteoglycan 2, HSPG, perlecan, perlecan proteoglycan, PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia), PRCAN, SJA, SJS, SJS1
Rat
IgG2a Kappa
0.02 mg
Store at 4C.
Monoclonal
This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
0.2mg/mL
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Purified
HSPG2
Murine EHS laminin preparation
Protein A or G purified
RUO
Primary
3339
Human, Mouse, Porcine, Fish, Monkey, Primate
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

For Research Use Only