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Rat anti-MHC Class II, Clone: M5/114.15.2, PE-Cy5, Novus Biologicals™

Rat Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP1430700.05MG

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Catalog No. NBP14307005

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MHC class II (I-A/I-E) Monoclonal specifically detects MHC class II (I-A/I-E) in Human, Mouse samples. It is validated for Flow Cytometry.


MHC Class II
Aqueous buffer, may contain carrier protein/stabilizer (proprietary) with 0.09% Sodium Azide
class II histocompatibility antigen, M alpha chain, D6S222E, DMA, HLA class II histocompatibility antigen, DM alpha chain, major histocompatibility complex, class II, DM alpha, MHC class II antigen DMA, Really interesting new gene 6 protein, RING6HLADM
IgG2b Kappa
0.05 mg
Adaptive Immunity, Asthma, Cell Biology, Diabetes Research, Immunology, Major Histocompatibility Complexes
Flow Cytometry
0.2 mg/mL
Flow Cytometry 1:10-1:1000
Affinity Purified
The immunogen for this antibody was MHC Class II.
Protein A or G purified
Store at 4C. Do not freeze.
The monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2 b, H-2 d, H-2 q, H-2 p, H-2 r and H-2 u but not from mice carrying the H-2 s or H-2 f haplotypes. The M5/114 mAb is reported to inhibit I-A-restricted T cell responses of the H-2 b, H-2 d, H-2 q, H-2 u but not H-2 f, H-2 k, or H-2 s haplotypes.
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