CD126 Rat anti-Mouse, Brilliant Violet 421, Clone: D7715A7, BD Optibuild™

Rat Monoclonal Antibody

Supplier:  BD Biosciences 740038

Catalog No. BDB740038

Description

The D7715A7 monoclonal antibody specifically binds to the mouse IL-6 receptor, which is also known as, CD126. The immunogen used to generate the D7715A7 hybridoma was OKT4 hybridoma cells. The D7715A7 hybridoma was selected based on its capacity to produce antibody that inhibited IL-6 binding to 2F4 cells (mouse B-cell hybridoma expressing high levels of IL-6 receptors). The binding of purified D7715A7 to B9 cells (mouse B-cell hybridoma expressing high levels of IL-6 receptors) is inhibited by recombinant mouse IL-6. This antibody has been reported to inhibit the in vitro and in vivo growth of the IL-6-dependent plasmacytoma line, T1033C2.

Specifications

• Antigen: CD126
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: Il6ra; IL-6 Receptor α chain; IL-6RA; IL-6R alpha
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Mouse
• Isotype: IgG2b κ

• Applications: Flow Cytometry
• Clone: D7715A7
• Conjugate: Brilliant Violet 421
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: OKT4 hybridoma cells
• Quantity: 50 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only