CD126 Rat anti-Mouse, Brilliant Violet 421, Clone: D7715A7, BD Optibuild™
Rat Monoclonal Antibody
Manufacturer: BD Biosciences 740038
The D7715A7 monoclonal antibody specifically binds to the mouse IL-6 receptor, which is also known as, CD126. The immunogen used to generate the D7715A7 hybridoma was OKT4 hybridoma cells. The D7715A7 hybridoma was selected based on its capacity to produce antibody that inhibited IL-6 binding to 2F4 cells (mouse B-cell hybridoma expressing high levels of IL-6 receptors). The binding of purified D7715A7 to B9 cells (mouse B-cell hybridoma expressing high levels of IL-6 receptors) is inhibited by recombinant mouse IL-6. This antibody has been reported to inhibit the in vitro and in vivo growth of the IL-6-dependent plasmacytoma line, T1033C2.
|Brilliant Violet 421|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Il6ra; IL-6 Receptor α chain; IL-6RA; IL-6R alpha|
|OKT4 hybridoma cells|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
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