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CD160 Rat anti-Mouse, Brilliant Violet 786, Clone: CNX46-3, BD Optibuild™
Rat Monoclonal Antibody
Supplier: BD Biosciences 741038
Description
The CNX46-3 monoclonal antibody specifically binds to mouse CD160, also known as Natural Killer Cell Receptor BY55. CD160 is a glycosyolphosphatidylinositol-anchored membrane glycoprotein that contains a single Ig domain. This member of the Ig Superfamily was the first identified as a MHC Class I antigen-specific Ig-like Receptor that was expressed by mouse NK cells. As a receptor, CD160 can bind to classical and non-classical MHC class I molecules with low affinity. As a ligand, CD160 can bind to HVEM (Herpes Virus Entry Mediator, a TNF Receptor Family Member). CD160 is expressed on a subset of NK cells, NKT cells, activated CD8+ T cells and TCR γδ T cells. The functions of CD160 have been reported to regulate NK cell activation both positively and negatively, depending on the stimulus.
The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).
Specifications
CD160 | |
Monoclonal | |
0.2mg/mL | |
Cd160; By55; Natural killer cell receptor BY55 | |
Rat | |
Affinity Purified | |
RUO | |
Mouse | |
IgG2a κ |
Flow Cytometry | |
CNX46-3 | |
Brilliant Violet 786 | |
Aqueous buffered solution containing ≤0.09% sodium azide. | |
Mouse CD160 Recombinant Protein | |
50 μg | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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