CD41 Rat anti-Mouse, Brilliant Violet 510, Clone: MWReg30, BD Optibuild™

Rat Monoclonal Antibody

Supplier:  BD Biosciences 740136

Catalog No. BDB740136

Description

The MWReg30 monoclonal antibody specifically binds to CD41, which is also known as glycoprotein IIb (gpIIb, GP IIb), Integrin α IIb chain, or Integrin alpha 2b. CD41 is a transmembrane glycoprotein that is encoded by Itga2b . CD41 associates with I ntegrin β3 chain (g pIIIa or CD61) to form the gpIIb/IIIa (CD41/CD61) complex. CD41/CD61 is expressed on platelets, megakaryocytes, and early hematopoietic progenitors. The integrin complex binds to fibrinogen, fibronectin, vitronectin, von Willebrand factor, and thrombospondin. It is important for platelet adhesion and aggregation, and it may play a role in osteolytic tumor metastasis.

Specifications

• Antigen: CD41
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: Itga2b; Integrin alpha 2b; Integrin alpha-IIb; Integrin α IIb; GpIIb
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Mouse
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: MWReg30
• Conjugate: Brilliant Violet 510
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Mouse Platelets
• Quantity: 50 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only