Ly-6G Rat anti-Mouse, Brilliant Violet 510, Clone: 1A8, BD Optibuild™
Rat Monoclonal Antibody
Manufacturer: BD Biosciences 740157
The 1A8 monoclonal antibody specifically binds to Ly-6G, a 21-25-kDa glycosyolphosphatidylinositol-anchored protein. In the bone marrow, Ly-6G is expressed on the majority of the largest cells, which are predominantly granulocytes, and not on lymphoid or erythroid cells. In the periphery, it is expressed on granulocytes. The RB6-8C5 monoclonal antibody recognizes both Ly-6G and Ly-6C and blocks the binding of mAb 1A8 to Ly-6G.
The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 405-nm and Em Max at 510-nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50-nm) filter set. BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser.
|Brilliant Violet 510|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|IgG2a, κ, also known as Lewis IgG2a, κ|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Ly6g; Lymphocyte antigen 6G; Lymphocyte antigen 6 complex, locus G; Gr1|
|Ly-6G-transfected EL4J cell line|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
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