Gibco™ Rat CNTF Recombinant Protein, PeproTech®

E. coli Recombinant Protein

Catalog Number	Mfr. No.	Quantity
45050100UG	Gibco™ 45050100UG	100 μg
450-50-1MG	Gibco™ 450501MG	1 mg
45050250UG	Gibco™ 45050250UG	250 μg
450-50-25UG	Gibco™ 4505025UG	25 μg
45050500UG	Gibco™ 45050500UG	500 μg
450-50-50UG	Gibco™ 4505050UG	50 μg
450-50-5UG	Gibco™ 450505UG	5 μg

Description

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.

Specifications

• Accession Number: P20294
• Formulation: protein with no preservative
• Molecular Weight (g/mol): 22.7
• Source: E. coli
• Regulatory Status: RUO
• Gene Alias: AI429687; Ciliary neurotrophic factor; ciliary neurotropic factor; Cntf; HCNTF; H-CNTF
• Specific Reactivity: Rat
• Recombinant: Recombinant
• Form: Lyophilized

• For Use With (Application): ELISA, Functional Assay, Western Blot
• Gene ID (Entrez): 25707
• Name: Rat CNTF
• Storage Requirements: -20°C
• Endotoxin Concentration: <1 EU/μg
• Gene Symbol: CNTF
• Conjugate: Unconjugated
• Sequence: AFAEQTPLTL HRRDLCSRSI WLARKIRSDL TALMESYVKH QGLNKNINLD SVDGVPVAST DRWSEMTEAE RLQENLQAYR TFQGMLTKLL EDQRVHFTPT EGDFHQAIHT LMLQVSAFAY QLEELMVLLE QKIPENEADG MPATVGDGGL FEKKLWGLKV LQELSQWTVR SIHDLRVISS HQMGISALES HYGAKDKQM
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.